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The Bench Scientist 42456 role at Makroscientific2 is an on-site position located in Andover.

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Bench Scientist 42456

Makroscientific2Andover2d ago

Quantitative cellular-Biomarker scientist

(Pharmacokinetics Dynamics & Metabolism) (contingent worker).skilled cell biologist/immunologist to join a state-of-the-art cellular biomarker-biomeasures laboratory in PDM, Expertise in cellular and functional assays using flow cytometry, cell culture and other immunological assays is required. The lab based role entails performing deep immune-phenotyping and phospho-signaling assays of human, mouse and cynomolgus cells, receptor quantification, receptor internalization, and receptor occupancy to support portfolio projects. This position requires deep knowledge of human and mouse immunology, proven expertise in multi-colorflow cytometry and biochemical techniques (antibody conjugation to fluorochromes) and a strong background in quantitative cell biology.Extensive experience with cell Biological techniques such as cell culture (cell lines as well as primary immune cells), cell isolation from human blood and mouse tissues, immune-staining for multi-color flow assaysis required,Expertise in the operation and maintenance of flow cytometers

Qualifications

BS/MS level education in immunology, cell biology or related fields required,3-6 years of experience in laboratory work in academic or industry setting.

Additional Information

Prepare and stain cells for receptor quantification, receptor internalization kinetics, immune-phenotyping, functional assays and microscopyRun flow assays under minimal supervision; initiative in method development is expected.Independentlycarry out daily operation,calibration,maintenance and trouble shooting of flowcytometers and time-lapse microscopes.Help in assay and reagent development, sample preparation and analysis for biomarker discovery using mass cytometry (CyTOF).Expertise in the operation and maintenance of microscopes (time-lapse and confocal).Expertise in biochemical assays using MSD and Octet platformsOpen to learning assays for biomarker analysis using mass spectrometry.

Bench Scientist 42456

Qualifications

Additional Information

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