Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.
Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work here.
Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine.
Our Vision
We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.
The Biohub invites exceptional scientists to apply for a Group Leader (Principal Investigator-equivalent) position. We seek researchers who pursue fundamental questions in immunology, including—though not limited to—experts in systems immunology, immune engineering, and functional or molecular immunology, with a particular emphasis on cellular subtypes associated with immune regulation in cancer and/or neuroinflammation. Ideal candidates will aim to uncover the core principles and dynamic behaviors that govern immune system function in both health and disease. We especially welcome applicants who integrate quantitative, high-throughput, and systems approaches to address broad immunological questions and principles, rather than those focused primarily on tool or method development. The overarching mission is to reveal the fundamental principles governing the function and development of the human immune system, including via regulatory, signaling, and cell-cell molecular interaction network analysis. The goal will be to identify mechanisms that can help reprogram the immune system’s function to monitor organ specific health conditions, modulate cell trafficking, and restore normal immune function in human disease conditions.
The Biohub in New York fosters a vibrant environment where fundamental discovery and cross-disciplinary collaboration are encouraged. We particularly welcome scientists eager to collaborate across biology, computation, and engineering to generate transformative insights into immune biology. The successful candidate will join a highly collaborative environment of both intramural investigators at the Biohub network and extramural investigators at our partner institutes, Columbia University, Yale University and The Rockefeller University. The successful candidate will have access to world-class resources within the Biohub and across partner campuses. Candidates are expected to establish an independent, creative and innovative research program, as well as demonstrate a commitment to collaboration. The Biohub will offer a competitive package with full funding for research personnel, lab operational costs, and essential equipment.
Applicants must hold a Ph.D., M.D., or equivalent degree in immunology or a related field, and have a strong foundation in quantitative or mechanistic approaches to biological research. Applicants should have a record of at least five years of postdoctoral or equivalent research experience demonstrating creativity, independence, and impactful contributions in research aligned with the themes described above.
Applicants are required to provide a cover letter and a 3-page research statement.
The New York City, NY base pay range for a new hire in this role is $153,000.00 - $185,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.
We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.
If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.
Interviews will begin starting April 15th 2026 and will continue until the position has been filled.
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