R&D Intern
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a R&D Intern as part of the Research & Early Development team based in Philadelphia, PA.
Role Overview
The R&D Intern will support research activities focused on cellular therapy and CAR-T technology. This role involves analyzing cytotoxic potential of CAR-T cells and other immune cells, performing cytokine analysis, and correlating donor variability. The intern will also assist in evaluating T cells generated with in-vivo CAR platforms and contribute to data analysis and reporting.
Key Responsibilities
- Perform cytotoxicity assays and cytokine analysis using MSD assay.
- Analyze CAR-T cells, macrophages, and other immune cells for cytotoxic potential.
- Correlate cytotoxicity data across multiple donors.
- Support in-vivo CAR platform evaluations.
- Analyze experimental data and prepare reports for manager and team.
- Maintain accurate laboratory records and follow SOPs.
Requirements
- College student (BS, MS, or PhD) in Life Science, Biomedical Science, Biotechnology, Cell Science, Biology, Virology, Molecular Biology, or STEM.
- Desired Academic Grade Level: Junior/Senior/ Graduate Student.
- Interest in cellular therapy and immunotherapy.
- Knowledge of CAR-T, virus design, or immune cell assays preferred.
- Ability to commit to lab bench work (70%) and desk work (30%).
- Strong communication and organization skills.
Skills You’ll Gain
- Hands-on experience in CAR-T cell culture and transduction.
- Exposure to in-vivo CAR platform development.
- Understanding of immunotherapy approaches and assay techniques.
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Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
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