In Vivo Lead
Summary
The In Vivo Lead will drive the design, execution, and interpretation of in vivo studies supporting radiopharmaceutical drug discovery and development programs at ARTBIO. This individual will provide both scientific and operational leadership, mentor team members, and ensure the generation of high-quality, timely data to inform key development decisions. The role requires close cross-functional collaboration with radiochemistry, biology, and discovery teams to define and advance the vision and capabilities for the vivo discipline at ARTBIO.
Responsibilities
Define and execute the strategic vision for the in vivo discipline, including recruiting, developing, and leading a high-performing team aligned with organizational goals
Foster strong partnerships within the broader Discovery organization, ensuring clear communication of priorities, timelines, and data delivery.
Identify technical or capacity gaps and proactively establish external collaborations to ensure delivery of critical, decision-enabling data.
Own the experimental rigor, data quality, and interpretation from the functional line by supporting technical development of the team and expansion of capabilities to increase efficiency (e.g., imaging, ICP-MS).
Continuously evolve in vivo capabilities to meet current and future portfolio needs.
Partner cross-functionally with the radiochemistry and discovery biology teams to support experimental design, understand the needs, and support in vivo studies.
Ensure strict adherence to Environment, Health & Safety (EHS) standards and Electronic Lab Notebook (ELN) compliance.
Establish and lead effective systems for resource planning and data sharing to support decision-making in a matrixed organization.
Qualifications & Education
PhD in pharmacology, biology, or related life science discipline with 7+ years of relevant postdoctoral and/or industry experience.
4+ years of leadership experience managing in vivo teams within oncology in a biotech, pharmaceutical, or CRO setting.
Demonstrated ability to think strategically and drive scientific innovation.
Experience with complex in vivo oncology models, including cell line–derived xenografts (CDX), patient-derived xenografts (PDX), and syngeneic models.
Experience in the identification, validation, and incorporation of translational biomarkers to elucidate mechanism of action.
Established track record as a scientific leader, including authorship of peer-reviewed publications and participation in oncology conferences.
Prior experience working with radiopharmaceuticals, including study design, execution, and interpretation of radioligand-based in vivo experiments.
About Us
Channeling Energy. Changing Lives. ARTBIO redefines cancer care by discovering and developing a new class of Alpha Radioligand Therapies (ARTs), powered by unique Pb-212 isotope technology and seamless supply. Our team works tirelessly to bring therapies that matter to patients who need them.
The unique ARTBIO approach selects the optimal alpha-precursor isotope (212Pb) and tumor-specific targets to create therapeutics with the potential for the highest efficacy and safety. The company's AlphaDirect™ technology, a first-of-its-kind 212Pb isolation method, enables a distributed manufacturing approach for the reliable production and delivery of ARTs. ARTBIO is advancing multiple pipeline programs, with lead program AB001 currently in first-in-human trials. The company is shaped by a long-standing scientific legacy with nearly a century of pioneering work in radiation therapy conducted at the University of Oslo and Norway’s Radium Hospital.
Cancer is relentless. So are we. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration. As an emerging, global biotech with locations in Boston, Basel, London, and Oslo, we take advantage of diverse scientific depth and insights, which makes ARTBIO a unique place to work.
EEO Statement
ARTBIO is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
Questions and Application Process
If interested, please apply and send your CV to HR@artbio.com. All inquiries are treated confidentially.
ARTBIO does not accept unsolicited resumes from external agencies or recruiters. Submission of a resume without a prior written agreement does not create any express or implied contract between ARTBIO and the agency. ARTBIO will not pay any fees related to unsolicited resumes.