Medical Science Liaison - Gene Therapy US Medical Affairs

Location: Remote, Central Territory US        

Reporting to: Senior Director, Medical Affairs – Americas              

Orchard Therapeutics, a Kyowa Kirin company, is a global gene therapy leader focused on transforming the lives of patients with rare disorders through innovative gene therapies based on gene-modified hematopoietic stem cells (HSCs). Orchard has its global headquarters in London, England, and its U.S. headquarters in Boston, Massachusetts.

Job Summary

The Medical Science Liaison (MSL) is a therapeutic and disease area scientific expert for investigational and approved gene therapy clinical programs. As a field-based member of the medical affairs team, the MSL will be responsible for developing and enhancing professional relationships with external thought leaders involved in all phases of the clinical development process through a fair-balanced and high-value exchange of clinical and scientific information. This position necessitates professionals exhibiting established personal and scientific credibility and self-awareness, who work well in a collaborative, cross-functional environment with other individuals within broader US and Global organization.

Key Responsibilities

·         Identify, build and maintain collaborative partnerships with healthcare providers (HCP’s) and key external experts such as KOL’s and academic institutions to become a trusted scientific partner.

·         Provide timely, audience-appropriate information and updates to enhance the understanding of the scientific and medical value of Orchard’s programs. This includes, but is not limited to, collaboration with Market Access, Government Affairs, Diagnostics, Patient Advocacy, Clinical Development etc.

·         Maintain training records and deliver training updates to ensure all personnel in assigned Qualified Treatment Centers are appropriately trained according to Orchard’s SOPs and the latest Product Manual.

·         Develop a territory profile including Centers of Excellence, key expertise, newborn screening approaches and leaders, and market access pathways to inform medical strategy and tactical planning in collaboration with our Commercial, Diagnostic, and Patient Advocacy partners.

·         Gather insights from the field on data, therapeutic area, and competitive intelligence to help inform company strategies and evidence generation plans.

·         Build thorough operational understanding to ensure excellence in execution balanced with risk management within the boundaries of all governance processes.

·         Review and oversee Investigator-Sponsored Trial (IST) requests and Early Access Program (EAP) requests throughout the internal review process and any follow up requests for information.

·         Build effective internal partnerships through communication and collaboration across the organization with individuals from Medical Affairs, Patient Advocacy, Public Affairs, Clinical Development, Clinical Operations, Technical Operations, Market Access, Commercial, etc.

·         Ensure compliance with internal and external regulatory and legal guidelines.

·         Maintain clinical, scientific, and technical expertise in therapeutic area.

Requirements

Education / Key Competencies

·         Advanced Scientific / Healthcare Degree (PhD, PharmD, MD, NP, DVM, CGC or similar preferred; RN, MS, or similar with substantial experience considered)

·         Minimum of 3-5 years experience in a scientific, clinical or MSL role within the biotech or pharmaceutical industry

·         Track record of successfully establishing relationships with health care provider thought leaders and extended clinical care teams to become a preferred point of contact and trusted resource.

·         Understanding of US government and industry guidelines, regulations, laws, etc., for appropriate and compliant exchange of scientific and clinical information with external stakeholders.

·         Experience and relevant knowledge in one or more key therapeutic areas: hematopoietic stem cell transplantation, gene therapy, and neurology/genetics (neurometabolic genetics preferred).

·         Experience in developing and delivering effective scientific educational materials and programs for multistakeholder/multispecialty audiences across disease states.

·         Strong knowledge and established network with health care providers and industry experts

·         Fluency in both spoken and written English

·         Excellent communication and presentation skills to concisely convey complex clinical and scientific information

·         Effective interpersonal skills and awareness of inward and outward emotional intelligence

·         Ability to apply technical expertise and solutions to diverse/individualized situations

·         Experience in achieving results, generating ideas and influencing outcomes through collaboration in a fast-paced environment.

·         Highly effective in building close working relationships with cross-functional partners

·         Growth mindset – curious by nature, proactive in keeping abreast of key scientific developments and building understanding of assigned territory

·         Valid US Driver’s License and clean driving record 

·         Ability to travel frequently (75%), often overnight