Senior Specialist, Clinical Supply Chain

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Independently support global clinical supply chain operations across multiple studies. This role is ideal for a detail-oriented, proactive professional who thrives in a fast-paced environment and can manage study-level supply planning, execution, and vendor coordination with minimal oversight.

• Independently manage clinical supply chain activities for assigned studies, including planning, execution, and reconciliation.

• Support global depot and site distribution, including coordination of Qualified Person (QP) release, import/export logistics, and temperature-controlled shipments.

• Lead clinical label design, packaging, and labeling activities in collaboration with internal teams and external vendors.

• Serve as the primary point of contact for CMOs, depots, and IRT vendors for assigned studies.

• Develop and maintain study-level supply plans and forecasts, adjusting for protocol amendments, enrollment trends, and country/site activation.

• Manage IRT system setup and maintenance, including drug assignment logic, inventory thresholds, and expiry management.

• Monitor and manage IP inventory across depots and sites, ensuring timely resupply and minimizing waste.

• Track and resolve temperature excursions, deviations, and other supply-related issues in collaboration with QA and vendors.

• Maintain study and depot-level accountability and reconciliation documentation to support regulatory compliance and study closeout.

• Collaborate cross-functionally with Clinical Operations, QA, Regulatory, and Project Management to ensure alignment and timely execution.

• Archive documentation on Trial Master Files as required.

Required Skills, Experience and Education:

• B.S. in a scientific or supply chain-related field.

• 3–6 years of experience in clinical supply chain and logistics, GMP manufacturing, Quality Assurance, or related pharmaceutical/biotech environment.

• Direct experience in production documentation review (MBRs, executed batch records, deviations, change controls), batch disposition and release processes, and QP certification of IMPs (Investigational Medicinal Products) and/or commercial products.

• Demonstrated experience supporting global clinical trials, including import/export logistics.

• Strong working knowledge of clinical packaging/labeling requirements and temperature-controlled distribution.

• Proficiency in Microsoft Excel. Veeva Quality Management System experience is a plus. 

• Experience with oncology trials and complex study designs is a plus.

• Excellent organizational, communication, and problem-solving skills.

• Ability to work independently while collaborating effectively across functions and with external partners.

Preferred Skills:

• Strong attention to detail and ability to critically review complex GMP documentation.

• Prior experience working within a Quality organization strongly preferred.

• Experience interacting with CMOs/external manufacturing partners. 

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