Sr. Director, Clinical Pharmacology

COMPANY INTRODUCTION

Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine.  We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.

As Sr. Director, Clinical Pharmacology, you will lead the design and execution of clinical pharmacology strategies across multiple programs, reporting directly to the Chief Medical Officer. You will serve as the subject matter expert for pharmacokinetics (PK), pharmacodynamics (PD), and modeling approaches to optimize dose selection and support regulatory submissions. On a day-to-day basis, you will oversee clinical pharmacology components of protocols, manage bioanalytical and PK/PD modeling activities, and collaborate with cross-functional teams to ensure robust data interpretation and compliance with regulatory standards. Given the novel biology studied by Triveni, you will have robust and frequent interactions with the research group to help develop the custom assays, elucidate PK/PD relationships, and ultimately lead the modeling necessary to ensure optimization of dose.  You must have broad experience in clinical pharmacology within the biopharmaceutical industry, including a proven track record of advancing programs through multiple phases.  Experience in the I&I space and experience with novel biology are strongly preferred.

This role offers exposure to strategic decision-making and the opportunity to influence the future of precision medicine in immunology and inflammation.

·         Define and implement clinical pharmacology strategies across multiple programs.

·         Lead PK/PD modeling, dose selection, and bioanalytical planning.

·         Author and review clinical pharmacology sections of protocols, regulatory documents, and submissions.

·         Collaborate with Clinical Development, Research, Regulatory Affairs, Biostatistics, and Clinical Operations to ensure integrated plans.

·         Represent Clinical Pharmacology in governance committees and regulatory interactions.

·         Oversee vendor management for bioanalytical and modeling activities.

·         Ensure adherence to GCP, ICH guidelines, and all applicable regulatory requirements.

·         Other duties as assigned.

·         Advanced degree (PhD, PharmD, or MD) in Clinical Pharmacology or related discipline required.

·         12+ years of experience in clinical pharmacology within the biopharmaceutical industry.

·         Experience with biologics and immunology/inflammation indications strongly preferred

·         Strong understanding of global regulatory requirements for clinical pharmacology.

·         Leadership experience managing cross-functional teams and external vendors.

The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.

We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.

Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio. Please disregard any other communication that does not originate from this domain name. If you receive any suspicious requests or communications, please verify their authenticity before responding.