Strategy & Operations
About Proxima
Proxima (formerly VantAI) is advancing an AI-native approach to drug discovery by making protein interactions programmable. Our platform brings together foundation-model machine learning, a scalable data generation engine, and a partnership track record exceeding $5B in collaborations across the world’s leading biopharma and tech organizations. We’ve recently closed an oversubscribed seed round partnering us with an elite group of sophisticated and dedicated VCs including DCVC, Nvidia’s Nventures, AIX, Yosemite among others.
Neo-1 is our all-atom foundation model that combines state-of-the-art structure prediction and molecular generation in a single system. Neo-1 enables rapid exploration of chemical and structural space for high value, previously intractable targets, and in particular unlocks small molecule proximity therapeutics like molecular glues with AI for the first time.
In parallel, we are developing an advanced structural interactomics platform built on proprietary XLMS technology and a lab equipped with next-generation mass spectrometry instrumentation. This platform produces proteome-scale maps of protein interactions and helps identify small molecules that modulate proximity. Together with Neo-1, it creates an integrated system capable of co-folding protein complexes while generating candidate small molecules to influence those interactions.
Proximity-based therapeutics represent one of most promising frontiers in modern drug discovery with the potential to treat previously intractable diseases and target ‘undruggable’ proteins. Our technology combines proteome-scale structural data with state-of-the-art generative AI foundation models, and coupled with our talented team of scientists and engineers we are uniquely well-positioned to discover and develop a new class of medicines. Come join us!
About You:
Proxima is seeking an individual to build the strategic and operational foundation for our next stage of growth. In this high-impact role, you will work directly with the C-Suite and broader leadership team to oversee critical R&D workflows, connect the dots across the organization, and ensure timely execution of our highest priority initiatives. You’ll drive strategy and operations for internal programs and our NeoLink platform, support key external relationships, own the management of our CRO portfolio, and set roadmaps and benchmarks that enable VantAI to remain at the top of our competitive landscape
Key Responsibilities:
Internal R&D Program Management – Oversee timelines, deliverables, and cross-functional coordination for high-priority internal R&D programs
NeoLink Platform Strategy – Support platform-related initiatives, from experiment planning to data integration and analysis, ensuring the science and operations run seamlessly
CRO Management - Oversee Proxima’s CRO portfolio ensuring alignment with program priorities and timelines
Operational Infrastructure – Build, optimize, implement processes, tools, and workflows that enhance communication, automate repetitive tasks, and keep the company operating at peak efficiency
Strategic & Competitive Insights – Conduct benchmarking, forecasting, strategy and competitive landscaping to inform decision-making, uncover opportunities, and identify potential risks
Manage relationships with Key Opinion Leaders (KOLs) and members of our Scientific Advisory Board
Basic Qualifications:
Bachelor’s or Master’s degree in a life sciences discipline, biology or chemistry preferred
3-5 years years’ experience in AI-driven drug discovery, CRO/vendor management, and/or data product management
Proficiency with Microsoft Excel, PowerPoint, Python, and GitHub
Strong analytical and problem-solving skills with a keen attention to detail
Excellent verbal and written communication skills, with the ability to present scientific information clearly to non-scientific stakeholders
Ability to work collaboratively in a fast-paced environment, manage multiple tasks, and meet deadlines
Preferred Qualifications:
Ability to influence senior-level management and key stakeholders is a plus
Strong sense of ownership and accountability; ability to manage multiple projects at once
Strategy & operations experience, ideally in a high-pressure multi-stakeholder environment (e.g., biotech, consulting, life sciences venture capital or private equity ...)
Excellent written and verbal communication skills, along with a strong desire to work in cross-functional teams
AI/Tech, Life Sciences and general business acumen with a comprehensive understanding of pharmaceutical or big-tech industries
Full-Time Employees at Proxima enjoy these Perks*:
Highly competitive salaries
Company Equity Package, everyone is a stakeholder!
401(k) + Company Match
Medical, Dental, & Vision Insurance (PPO w/ HSA & FSA options)
13 Paid Holidays + Unlimited PTO & Sick Time
Maternity leave 18 Weeks of fully paid leave + 6 weeks for Paternity leave
In-Office Lunch (5 days per week)
*for US based FTEs, country specific benefits apply for locations outside US