Development Specialist II
Description
Primary Role:
- This individual will contribute to purification process development.
- They will be responsible for performing laboratory and pilot scale column chromatography, Tangential flow filtration and analytical assays to support protein purification process development.
- The individual applies basic knowledge form various technical areas, industry practices and standards. Provides quality and productive output that is consistently timely, reliable and reproducible.
- The candidate must be customer focused, results oriented, science driven and embrace Shire’s values.
Responsibilities:
• Perform batch mode and column chromatography in support of purification process development –35 %
• Perform ultrafiltration and diafiltration in support of purification process development – 35%
• Analyze, summarize and document data – 20%
• Interact with analytical development and cell culture groups as well as development and engineering groups to ensure proper information exchange – 10%
Report any unexpected observations and suggest possible explanations and resolutions.
Present data in group forums; suggest conclusions and experimental plans based on purification fundamentals.
Examine literature and provide summaries in support of interpretations for experimental outcomes.
Report to supervisor in the purification group within BioProcess Development group. .
Qualifications
Education & Experience Requirements:
- • MS (0-2 years) or BS (2+ years) in Chemical/Biochemical Engineering or related discipline with relevant industry experience.
- • Product and purification process development experience in the biotechnology/pharmaceutical industry with practical experience around scale-up, technology transfer and manufacturing support of large scale GMP operations is desired.
- • Familiarity with the operation of large scale purification equipment for chromatographic and filtration unit operations is desired.
- • Engineering degree preferred.
- • Keeps current with literature and latest technology developments, particularly in the area of separations.
Skills:
- • Experience and knowledge in protein purification process development, including TFF, ion-exchange, affinity, mixed mode and HIC column chromatography.
- • Experience in protein analytical methods, including spectrophotometry, ELISA, HPLC, enzymatic assays, SDS-PAGE and Western Blot.
- • Demonstrated capability of high quality work and keen attention to detail.
- • Proficiency in Microsoft Word and Excel.
- • Strong interpersonal and communication skills.
- • Self-motivated and highly adaptable to rapidly changing priorities.
- • Ability to work as a team player to achieve departmental and company goals under tight timeline requirements.
Additional Information
All your information will be kept confidential according to EEO guidelines.
IF THIS IS THE JOB OPPORTUNITY FOR YOU GIVE ME A CALL AT 646-357-1104 ASAP!
I look forward to hearing from you!