Medical Director, Clinical Development

Role Summary
We are seeking a driven and strategic Medical Director, Clinical Development to lead clinical development efforts across one or more early- or late-stage programs. This pivotal role offers the opportunity to shape clinical strategy, serve as medical monitor, and collaborate cross-functionally to drive execution. Depending on business needs, the role may also include mentoring clinical scientists and contributing to business development and process improvement initiatives.

Key Responsibilities

Clinical Development Leadership (75%)

• Lead clinical strategy and execution for one or more programs; serve as medical monitor and oversee study-level activities.
• Conduct data review in collaboration with clinical science and safety; author clinical and regulatory documents (e.g., protocols, IBs, INDs).
• Engage with KOLs, lead advisory boards and steering committees, and support publications.
• Present findings to leadership and contribute to the scientific and commercial advancement of pipeline assets.

Organizational Contribution & Cross-Functional Collaboration (25%)

• Partner cross-functionally to drive alignment, communication, and operational excellence across teams as well as between Ono and Deciphera.
• Contribute clinical insights to target assessments, business development, and strategic initiatives.
• Support Medical Affairs and serve as a clinical liaison for study sites and internal teams.
• Participate in continuous improvement efforts and help foster a collaborative company culture.

Qualifications

Required Qualifications

• MD (or equivalent) with 8+ years of academic/industry experience, including 3+ years in clinical trials
• Proven experience in trial design, execution, and medical monitoring
• Strong understanding of GCP/ICH and global regulatory standards
• Familiarity with data review tools (e.g., Rave, J-Review, Spotfire)
• Excellent leadership, communication, and cross-functional collaboration skills
• Ability to work across time zones and up to 30% travel

Preferred Experience

• Board-certified in Medical Oncology
• Experience across Phases 1–3 of clinical development
• Direct interaction with U.S. and ex-U.S. regulatory agencies
• Background in basic or translational research

Additional Information

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $243,300 - $334,590. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.​

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially.  We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.