Senior Medical Director, Clinical Development

Role Summary

We are seeking a dynamic and strategic Senior Medical Director, Clinical Development to join our Clinical Development team. This critical leadership role will provide clinical direction across one or more programs in early and/or late-stage development, while also representing Clinical Development in business development activities. The ideal candidate will be highly collaborative, scientifically rigorous, and passionate about bringing innovative therapies to patients.

With responsibilities spanning clinical strategy, medical monitoring, cross-functional collaboration, and external engagement, this individual will play a key role in driving enterprise goals forward. Depending on business needs, this role may include mentorship and management of clinical scientists.

Key Responsibilities

Clinical Development Leadership (50%)

• Lead clinical strategy and execution for early- and late-stage programs.
• Serve as medical monitor and oversee data review and clinical documentation.
• Build KOL relationships, lead advisory activities, and support external publications.
• Present findings to leadership and mentor clinical team members as needed.

Cross-Functional Collaboration & Organizational Growth (50%)

• Represent Clinical Development in business development and due diligence efforts.
• Provide clinical input for new targets, strategic planning, and internal initiatives.
• Collaborate cross-functionally and support alliance integration with partners.
• Act as a clinical resource for internal teams and study sites.

Qualifications

Required Qualifications

• MD (or equivalent) with 10+ years of academic/industry experience, including 5+ in biotech/pharma
• Proven track record in trial design, execution, and medical monitoring
• Strong knowledge of GCP/ICH and regulatory guidelines; FDA interaction experience
• Skilled in data review tools (e.g., Rave, J-Review, Spotfire)
• Recognized within the medical/scientific community with strong communication and leadership skills
• Comfortable in cross-functional, fast-paced environments; able to travel up to 30%

Preferred Experience

• Board-certified in Medical Oncology
• Experience across Phases 1–3 of clinical development
• Involvement in business development or due diligence, especially in oncology, neurology, or immunology
• Global regulatory experience outside the U.S.
• Background in basic or translational research

Additional Information

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $289,000 - $397,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.​

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially.  We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.