Scientist III/Sr. Scientist, Strain Engineering (Singapore)
Who We Are:
Antheia is a science and technology company developing next generation plant-inspired medicines. Applying synthetic biology, genomics, bioinformatics, data science, and fermentation, we harness the most beneficial molecules from plants to create active pharmaceutical ingredients in more controlled and economical ways. We are a close-knit team inspired by the possibilities of delivering transformative technologies and breakthrough science to change the course of medicine. We value our people as our most important resource and are always looking for talented individuals who can make valuable contributions to our efforts.
The Scientist in Strain Engineering is a highly motivated scientist working to engineer microbial strains for the production of valuable natural products. They have a strong background in DNA assembly and genetic engineering techniques as well as microbial metabolism and physiology. The ability to communicate well, and to interact with others in a small, dynamic and fast-paced environment, is essential.
Responsibilities Include:
- Engineer microbial strains for the production of valuable natural products
- Design and evaluate expression and activity of new enzymes and entire pathways
- Develop and test metabolic engineering strategies to improve key performance metrics
- Evaluate engineered strains in small scale assays and work closely with the fermentation team to validate strains in tanks
- Critically evaluate data to understand how strain genotype effects small and large scale performance and physiology
- Develop and/or introduce new methods to increase throughput and efficiency of DNA construction and genetic engineering
- Perform other duties as assigned[1]
Qualifications/Experience:
- D in molecular biology, microbiology, chemical engineering, bioengineering or a related field, or Master’s with 7+ years of industrial experience
- Proven track record of genetic engineering of microorganisms
- Solid understanding of yeast and microbial metabolism, physiology, and fermentation
- Experience with diverse microbial hosts preferred
- Experience with high-throughput screening, directed evolution, CRISPR/Cas9 and advanced cloning techniques preferred
- Experience with enzyme engineering and biochemistry preferred
- Experience with natural product biosynthesis, enzymology, and characterization a plus
[1] This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned at any time with or without notice.
Please note that Antheia doesn't discriminate based on age, race, ethnicity, national origin, religion, gender, sexual orientation, disability, medical history, and other non-merit characteristics.
For full-time employees, Antheia offers a comprehensive total rewards package. Part-time (<30 hours per week) and temporary roles are not eligible for Company sponsored benefits.
- Comprehensive compensation package, which includes annual bonus potential and equity opportunities
- Paid time off, in addition to company-observed holidays
- Excellent medical, dental, and vision insurance
- 401(k) retirement savings plan
- Free access to the Menlo Park Labs Gym
- Menlo Park Labs free shuttle service to CalTrain, BART Station, and SF
Antheia is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Antheia prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws.
Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire..