Senior Research Associate, Strain Engineering - SINGAPORE
Who We Are:
Antheia is a science and technology company developing next generation plant-inspired medicines. Applying synthetic biology, genomics, bioinformatics, data science, and fermentation, we harness the most beneficial molecules from plants to create active pharmaceutical ingredients in more controlled and economical ways. We are a close-knit team inspired by the possibilities of delivering transformative technologies and breakthrough science to change the course of medicine. We value our people as our most important resource and are always looking for talented individuals who can make valuable contributions to our efforts.
The purpose of this position is to engineer and optimize yeast to produce valuable plant natural products for the pharmaceutical industry. The employee will be part of an interdisciplinary, dynamic and enthusiastic team and must demonstrate a high degree of flexibility, creativity and initiative. The employee should have a strong desire and ability to learn and contribute as both a leader and team player within a cross-functional project team.
Responsibilities include:
- Engineering yeast strains for the production of valuable plant natural products
- DNA design and construction
- Yeast DNA transformation, strain verification, and testing
- Developing independent hypotheses, experimental strategy, and strain designs
- Optimizing growth and production conditions in microtiter plates
- Evaluating engineered strains in small scale assays and working closely with the fermentation team to validate strains in tanks
- Working closely with the enzyme engineering group to build screening strains and incorporate improved protein sequences
- Analyzing data, document results, developing SOPs, preparing presentations and written reports, and communicating ideas and results clearly
- Performing other duties as assigned[1]
Qualifications/Experience:
- B.S. or M.S. degree in biology, biochemistry, molecular biology, chemical engineering or a related field
- 6+ years of relevant laboratory experience conducting research with engineered microbes is preferred
- Proficiency with Molecular Biology and genetic engineering methods including PCR, primer design, genomic DNA/plasmid DNA isolation, gel electrophoresis, restriction digest, cloning, DNA sequencing, and strain verification by PCR analysis
- Familiar with techniques used for DNA construction and assembly, DNA transformation into E.coli and S. cerevisiae
- Experience with culturing microbial organisms in microtiter plates and shake flasks
- Experience with protein engineering is a plus
[1] This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned at any time with or without notice.
Please note that Antheia doesn't discriminate based on age, race, ethnicity, national origin, religion, gender, sexual orientation, disability, medical history, and other non-merit characteristics.
For full-time employees, Antheia offers a comprehensive total rewards package. Part-time (<30 hours per week) and temporary roles are not eligible for Company sponsored benefits.
- Comprehensive compensation package, which includes annual bonus potential and equity opportunities
- Paid time off, in addition to company-observed holidays
- Excellent medical, dental, and vision insurance
- 401(k) retirement savings plan
- Free access to the Menlo Park Labs Gym
- Menlo Park Labs free shuttle service to CalTrain, BART Station, and SF
Antheia is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Antheia prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws.
Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire..