Scientist II/Senior Scientist I, Biologics Generation Group

 Abbvie has an opening for a Scientist II/Senior Scientist I, Biologics Generation Group at our Bioresearch Center in Worcester, MA. The Biologics Generation Group collaborates with drug discovery project teams across all Abbvie therapeutic areas including Oncology, Immunology, and Neurology. The ideal candidate will effectively work in cross-functional teams to produce and characterize biopharmaceutical products, such as fully-human monoclonal antibodies, and novel multi-specifics including dual variable domain immunoglobulin (DVD-Ig™). They will have expertise in protein analytical techniques such as mass spectrometry, chromatography, differential scanning calorimetry, etc.

Key Responsibilities:

• Develop advanced analytical methods to characterize biologics using mass spectrometry and UHPLC
• Design and execute assays for high throughput drug-like property assessment of biologics
• Impact projects through protein production and screening of recombinant biopharmaceutical candidates in high throughput
• Demonstrate scientific excellence, work ethic, and dedication to team and project goals
• Work collaboratively in a matrix with project teams and members of the Biologics Generation Group to drive innovation and deliver novel therapies to our patients
• Develop productive collaborations and communication with other groups, across therapeutic areas

Qualifications

• Bachelor’s degree in related discipline with 7 or more years of experience or Master’s degree with 5 or more years of experience
• Expertise in protein analytical techniques for the assessment of drug-like properties of biopharmaceutical candidates
• Experience maintaining instrumentation and method development for protein and peptide mass spectrometry
• Experience working with automated laboratory workflows and instruments such as Hamilton and Tecan liquid handlers
• Experience with transient protein expression and purification
• Experience with assays such as ELISA and flow cytometry

Preferred Qualifications:

• PhD in related discipline with no experience necessary

Additional Information

All your information will be kept confidential according to EEO guidelines.